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Triptorelin, [DTrp6]-LH-RH, Amide

Name
Triptorelin, [DTrp6]-LH-RH, Amide
Molecular structural formula
Purity
≥95%
CAS Number
57773-63-4
Formula
C64H83N18O13
MW
1311.5
Sequence
Glp-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
Sequence Shortening
{Glp}-HWSY-{D-Trp}-LRPG-NH2
InChIKey
VXKHXGOKWPXYNA-PGBVPBMZSA-N
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Triptorelin is an oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone. It has a role as a gonadotropin releasing hormone agonist, an antineoplastic agent and a contraceptive drug.Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men.